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Chest, Vol 100, 847-848, Copyright © 1991 by American College of Chest Physicians


ARTICLES

Tranexamic acid treatment of hemothorax in two patients with malignant mesothelioma

WA De Boer, MG Koolen, CM Roos and JW Ten Cate
Academic Medical Center, Amsterdam, The Netherlands.

Patients with malignant mesothelioma may present with hemothorax. We used a combination of oral and intrapleural tranexamic acid to treat two patients with this severe complication. Initiation of treatment with this potent anti-fibrinolytic drug resulted in rapid reduction of bleeding and of transfusion requirements.


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