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Chest, Vol 101, 8-11, Copyright © 1992 by American College of Chest Physicians

ARTICLES

Lung transplantation of ventilator-dependent patients. The Washington University Lung Transplantation Group

DE Low, EP Trulock, LR Kaiser, MK Pasque, NA Ettinger, C Dresler and JD Cooper
Department of Surgery, Washington University School of Medicine, St. Louis 63110.

During the last few years, lung transplantation has been extended to patients with a variety of end-stage lung diseases, but recipient selection guidelines have remained relatively strict. Ventilator- dependent patients have traditionally been considered poor candidates for transplantation. However, patients who have been thoroughly evaluated and accepted for transplantation and subsequently develop respiratory failure caused by progression and/or exacerbation of their underlying disease and recipients who experience respiratory failure caused by graft failure may be suitable candidates while ventilator- dependent if no other major complications or contraindications arise before a donor organ becomes available.


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