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Chest, Vol 101, 366-370, Copyright © 1992 by American College of Chest Physicians

ARTICLES

Acute silicosis responding to corticosteroid therapy

GB Goodman, PD Kaplan, I Stachura, V Castranova, WH Pailes and NL Lapp
Department of Medicine, West Virginia University, Morgantown.

The course of acute silicosis usually is relentlessly progressive. Death results from cor pulmonale and respiratory failure, with mycobacterial infection a frequent serious complication. Attempts to treat the illness generally have been unavailing. We report an unusual case of acute silicosis in which improvement in clinical status, chest x-ray film findings and pulmonary function occurred following therapy with corticosteroids. To our knowledge, this is the first such case reported in the medical literature.


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