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Chest, Vol 102, 1323-1327, Copyright © 1992 by American College of Chest Physicians


ARTICLES

Bronchoalveolar lavage in trauma patients for diagnosis of fat embolism syndrome

JM Vedrinne, C Guillaume, MC Gagnieu, P Gratadour, C Fleuret and J Motin
Service d'Anesthesie-Reanimation, Hopital Edouard Herriot, Lyon, France.

Fat embolism syndrome (FES) is a rare but serious complication occurring after long bone fractures. Presence of fat droplets in cells obtained by bronchoalveolar lavage has been proposed as a specific tool for FES diagnosis in trauma patients. We evaluated this technique over a 15-month period in 85 patients. Twenty-eight patients were excluded. The remaining 57 patients were divided into three groups: group 1, 26 patients without trauma as control; group 2, 22 patients with trauma but without evidence of FES; and group 3, nine patients with trauma and evidence of FES. Six of 26 patients in group 1 and nine of 22 patients in group 2 exhibited fat droplets in alveolar macrophages, whereas three of nine patients of group 3 had not. This study suggests that (1) presence of fat droplets in alveolar macrophages is not a reliable method for diagnosis of FES after long bone trauma, and (2) many conditions are associated with fat droplets in alveolar macrophages.


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Ann. Thorac. Surg.Home page
D. A. Waller, M. K. Bennett, P. A. Corris, and J. H. Dark
Donor-Acquired Fat Embolism Causing Primary Organ Failure After Lung Transplantation
Ann. Thorac. Surg., June 1, 1995; 59(6): 1565 - 1566.
[Abstract] [Full Text]




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Copyright © 1992 by the American College of Chest Physicians.