Chest ACCP Education Calendar
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Guest Access | Sign In via User Name/Password
This Article
Right arrow Full Text (PDF) Free
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Article Archive
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Mann, M. C.
Right arrow Articles by ZuWallack, R. L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Mann, M. C.
Right arrow Articles by ZuWallack, R. L.

Chest, Vol 102, 1342-1346, Copyright © 1992 by American College of Chest Physicians

ARTICLES

An evaluation of severity-modulated compliance with q.i.d. dosing of inhaled beclomethasone

MC Mann, O Eliasson, K Patel and RL ZuWallack
Section of Pulmonary Diseases, Saint Francis Hospital and Medical Center, Hartford, Conn.

Although the asthmatic subject's compliance with a regimen of inhaled corticosteroids is often poor, it has been suggested this may improve during periods of increased severity. To test this, we measured daily peak expiratory flow rates (PEFRs), asthma symptoms, and the use of an albuterol inhaler over nine weeks period in ten patients with moderately severe asthma. The effect of changes in these severity indices on compliance with a q.i.d. regimen of inhaled beclomethasone was evaluated. The PEFR was measured in the morning before bronchodilator administration, and symptoms were graded on a scale of 4 to 16, while albuterol and beclomethasone inhalations were electronically recorded. Three measures of compliance with the beclomethasone regimen were used: (1) mean daily compliance ([number of inhalations/number of prescribed inhalations] x 100); (2) underuse, ie, the percentage of days with less than the prescribed number of inhalations; and (3) overuse, ie, the percentage of days with greater than the prescribed number of inhalations. Mean daily compliance was 67 +/- 36 percent, while underuse was observed in 69 percent and overuse in 11 percent of the days. Despite clinical exacerbations in six of the ten patients and considerable variation in the severity indices, no significant relationship was found between the change in asthma severity and compliance with the beclomethasone regimen. These findings do not support the concept of severity-modulated compliance with inhaled corticosteroids.


This article has been cited by other articles:


Home page
 ChestHome page
M. G. Cochrane, M. V. Bala, K. E. Downs, J. Mauskopf, and R. H. Ben-Joseph
Inhaled Corticosteroids for Asthma Therapy: Patient Compliance, Devices, and Inhalation Technique
Chest, February 1, 2000; 117(2): 542 - 550.
[Abstract] [Full Text] [PDF]

Home page
 Psychosom. Med.Home page
G. Affleck, A. Apter, H. Tennen, S. Reisine, E. Barrows, A. Willard, J. Unger, and R. ZuWallack
Mood States Associated With Transitory Changes in Asthma Symptoms and Peak Expiratory Flow
Psychosom Med, January 1, 2000; 62(1): 61 - 68.
[Abstract] [Full Text] [PDF]

Home page
 NEJMHome page
J. Weiner, M. Abramson, R. Puy, J. Wilson, J. M. Portnoy, I. Finegold, T. A.E. Platts-Mills, J. S. Klein, F. Chmelik, A. Doughty, et al.
Ragweed Immunotherapy in Adult Asthma
N. Engl. J. Med., July 18, 1996; 335(3): 203 - 206.
[Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1992 by the American College of Chest Physicians.