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Chest, Vol 103, 958-960, Copyright © 1993 by American College of Chest Physicians

ARTICLES

Liver cirrhosis with severe hypoxemia and paradoxic pulmonary vascular response to graded inspiratory oxygen tension

S Kobayashi, A Aida, K Aoi, M Nishimura and Y Kawakami
First Department of Medicine, Hokkaido University School of Medicine, Sapporo, Japan.

We present the findings in a patient with liver cirrhosis who showed oppositional pulmonary vascular responses to various alveolar oxygen tensions. In this case the pulmonary artery constricted on exposure to hyperoxia and then gradually dilated during progressive hypoxic inhalation. Such a paradoxic response must result in severe arterial hypoxemia because of severe V/Q mismatching.




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Copyright © 1993 by the American College of Chest Physicians.