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Chest, Vol 103, 1118-1119, Copyright © 1993 by American College of Chest Physicians

ARTICLES

Cerebral hemodynamics in obstructive sleep apnea

M Siebler and A Nachtmann
Department of Neurology, Heinrich-Heine-Universitat, Dusseldorf, Germany.

We have investigated cerebral blood flow velocity (CBVF) in 14 patients with marked obstructive sleep apnea syndrome using transcranial Doppler ultrasonography during sleep. The CBFV increased during apnea, with a mean acceleration of 0.9 cm/s2, followed by a rapid decrease during snoring. The same effect was obtained by voluntary apnea in healthy subjects, showing a smaller acceleration rate (0.6 cm/s2). These results provide evidence for a normal CO2 regulation of cerebral vessels during sleep apnea and do not support the notion of cerebral hypoperfusion during sleep being a risk factor for stroke.


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 Am. J. Respir. Crit. Care Med.Home page
A. I. QURESHI, W. CHRISTOPHER WINTER, and D. L. BLIWISE
Sleep Fragmentation and Morning Cerebrovasomotor Reactivity to Hypercapnia
Am. J. Respir. Crit. Care Med., October 1, 1999; 160(4): 1244 - 1247.
[Abstract] [Full Text]


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Copyright © 1993 by the American College of Chest Physicians.