Chest Email Content Delivery
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Guest Access | Sign In via User Name/Password
This Article
Right arrow Full Text (PDF) Free
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Article Archive
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Kales, S. N.
Right arrow Articles by Christiani, D. C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kales, S. N.
Right arrow Articles by Christiani, D. C.
(Chest. 1994;106:147-150.)
© 1994 American College of Chest Physicians

Carboxyhemoglobin Levels in Patients With Cocaine-related Chest Pain

Stephen N. Kales M.D., M.P.H.1; James Feldman M.D.2; Lewis Pepper M.D., M.P.H.3; Susan S. Fish Pharm. D., M.P.H.4; David Ozonoff M.D., M.P.H.3; and David C. Christiani M.D., M.P.H., M.S., F.C.C.P.5

1 From the Department of Environmental Health, Harvard School of Public Health; and Harvard Medical School, Cambridge, Mass
2 From the Department of Medicine, Boston University School of Medicine, Boston
3 From the Department of Environmental Health, Boston University School of Public Health, Boston
4 From the Division of Sociomedical Sciences and Community Medicine, Emergency Medicine, Boston University School of Medicine, Boston
5 From the Department of Environmental Health, Harvard School of Public Health, Cambridge, Mass

Carboxyhemoglobin (COHb) levels were measured in patients who came to an emergency department complaining of acute chest pain. For subjects not receiving prior oxygen therapy, those with cocaine-related chest pain (n=10) had a higher mean COHb level than a comparison group (n=28) with nonischemic chest pain (4.50±2.40 vs 2.73±0.66; p<0.05). Four of the seven (57 percent) who smoked crack had COHb levels greater than 4.5 percent, while only one of six (17 percent) smokers of only tobacco had such a level. These findings suggest an additional mechanism, the formation of COHb, which could aggravate cocaine-induced cardiotoxicity.

Key Words: angina pectoris • carboxyhemoglobin • cardiac ischemia • chest pain • cocaine

Submitted on July 15, 1993
Accepted on December 27, 2007






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1994 by the American College of Chest Physicians.