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(Chest. 1994;106:594-600.)
© 1994 American College of Chest Physicians

Cardiovascular Manifestations of Cocaine Abuse

A Case of Recurrent Dilated Cardiomyopathy

Howard J. Willens M.D.1; Simon C. Chakko M.D.1; and Kenneth M. Kessler M.D.1

1 From the Division of Cardiology, Department of Medicine, University of Miami School of Medicine, the Cardiology Section, Medical Service, Department of Veterans Affairs Medical Center, Miami, Fla, and Memorial Hospital, Hollywood, Fla.

The medical complications of cocaine abuse are being encountered by clinicians with increasing frequency. The cardiovascular manifestations of cocaine abuse include chest pain, myocardial ischemia and infarction, congestive heart failure, arrhythmias, infective endocarditis, and aortic dissection. The pathogenesis of these cardiovascular complications has not been fully elucidated but may be related to a combination of the sympathomimetic and membrane anaesthetic effects of cocaine. We present these concepts in a case discussion format.

Key Words: Cocaine abuse • congestive heart failure • dilated cardiomyopathy




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Copyright © 1994 by the American College of Chest Physicians.