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(Chest. 1994;106:640-642.)
© 1994 American College of Chest Physicians

Bronchogenic Carcinoma in Patients Seropositive for Human Immunodeficiency Virus

Shawn D. Aaron M.D.1; Ellen Warner M.D.1; and Jeffrey D. Edelson M.D., F.C.C.P.1

1 From the Department of Medicine, St. Michael's Hospital, University of Toronto, Ontario, Canada

The purpose of this report is to describe an association between bronchogenic carcinoma and HIV. Three HIV-seropositive patients are described who developed bronchogenic cancer (two large cell, one adenocarcinoma) before developing an AIDS-defining illness. A critical review of the literature revealed 22 other patients in which the association of HIV infection and lung cancer is reported. These patients are characterized by a relatively young age at diagnosis (median, 43 years) and prevalence of the adenocarcinoma subtype (13 of 25 patients). Twenty of 21 patients had a history of smoking. Among 21 patients for whom data were available, 6 patients (28 percent) had AIDS at time of diagnosis of lung cancer while 11 patients (55 percent) did not have AIDS or AIDS-related complex at diagnosis.




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Copyright © 1994 by the American College of Chest Physicians.