Chest ACCP Career Connection
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Guest Access | Sign In via User Name/Password
This Article
Right arrow Full Text (PDF) Free
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Article Archive
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Sharifi, M.
Right arrow Articles by Silverman, I. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Sharifi, M.
Right arrow Articles by Silverman, I. M.
(Chest. 1995;107:36-40.)
© 1995 American College of Chest Physicians

Myocardial Infarction With Angiographically Normal Coronary Arteries

Mohsen Sharifi MD1; Thomas G. Frohlich MD1; and Irwin M. Silverman MD1

1 From the Division of Cardiology, Department of Medicine, Evanston Hospital, Northwestern University Medical School, Evanston, Ill

To determine the prevalence rate and clinical and hemodynamic profile of patients with myocardial infarction (MI) with angiographically normal coronary arteries, we analyzed 3,403 consecutive angiograms performed within a 4.5-year period. Of these studies, 1,124 were performed following an acute MI. Through a computerized search, 12 patients were identified who had documented MI with normal or insignificant (<30% stenosis in one epicardial vessel only) coronary disease. Q-wave MI developed in five patients (group A) and non-Q-wave MI developed in seven patients (group B). Group A patients were all men whereas group B patients were all women. Overall, group A patients were younger (p=0.003), had a longer smoking history (p=0.008), and a higher cardiac index (p=0.005). In ten patients, areas of localized dyskinesia or hypokinesia were shown on left ventricular cineangiography. Mitral valve prolapse was present in four of the patients and varying degrees of mitral regurgitation were identified in another six. The prevalence rate of MI with angiographically normal coronary arteries was 1% in this study. This entity had a bimodal age and sex distribution: a younger age group, all men, with a stronger cigarette smoking history who had Q-wave MI vs an older age group, all women, and no significant association with cigarette smoking who developed non-Q-wave MI. A mean follow-up of 4 years demonstrated a favorable prognosis in both groups.

Key Words: coronary angiography • coronary artery disease • mitral regurgitation • mitral valve prolapse • myocardial infarction

Submitted on January 12, 1994
Accepted on May 16, 2007




This article has been cited by other articles:


Home page
 JRSMHome page
B Chandrasekaran and A S Kurbaan
Myocardial infarction with angiographically normal coronary arteries
J R Soc Med, January 8, 2002; 95(8): 398 - 400.
[Full Text] [PDF]

Home page
 Eur Heart JHome page
J.S. Alpert
Fascination with myocardial infarction and normal coronary arteries
Eur. Heart J., August 2, 2001; 22(16): 1364 - 1366.
[PDF]

Home page
 Eur Heart JHome page
A Da Costa, K Isaaz, E Faure, S Mourot, A Cerisier, and M Lamaud
Clinical characteristics, aetiological factors and long-term prognosis of myocardial infarction with an absolutely normal coronary angiogram; a 3-year follow-up study of 91 patients
Eur. Heart J., August 2, 2001; 22(16): 1459 - 1465.
[Abstract] [PDF]

Home page
 J Am Coll CardiolHome page
N. S. Van de Water, J. K. French, M. Lund, T. A. Hyde, H. D. White, and P. J. Browett
Prevalence of factor v leiden and prothrombin variant g20210a in patients age <50 years with no significant stenoses at angiography three to four weeks after myocardial infarction
J. Am. Coll. Cardiol., September 1, 2000; 36(3): 717 - 722.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
P. Ammann, S. Marschall, M. Kraus, L. Schmid, W. Angehrn, R. Krapf, and H. Rickli
Characteristics and Prognosis of Myocardial Infarction in Patients With Normal Coronary Arteries
Chest, February 1, 2000; 117(2): 333 - 338.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1995 by the American College of Chest Physicians.