| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
Guest Access | Sign In via User Name/Password
|
|
|
|||||||
Guest Access | Sign In via User Name/Password |
|||||||||
1 From the Department of Internal Medicine, St. Boniface Hospital, Winnipeg, Manitoba
2 From the Department of Medical Microbiology, St. Boniface Hospital, Winnipeg, Manitoba
3 From the National Center for Streptococcus, Provincial Laboratory of Public Health for Northern Alberta, Edmonton, Alberta
4 From the Department of Health Sciences Centre, St. Boniface Hospital, Winnipeg, Manitoba
Study objective: To review experience with pneumococcal bacteremia at two Canadian tertiary care centers.
Design: Retrospective record review.
Setting: Two tertiary acute care teaching hospitals in Winnipeg, Manitoba.
Patients: Patients identified with pneumococcal bacteremia during an 8-year period.
Results: Hospital records were reviewed for 534 of 617 patients with pneumococcal bacteremia. The overall case fatality ratio was 70 (13%), varying from 3.2% in children to 43% in those older than 80 years. Twenty-seven (18%) hospitalized children and 68 (23%) adults required ICU admission. Duration of hospitalization was 14.9±24.9 and 11.0±19.1 days for children at the two institutions and 22.5±37.6 days and 38±93 days for adults. For the 217 viable pneumococcal strains studied, 89% were serotypes included in the present 23-valent vaccine. Documentation of prior vaccination was present for only 9 (1.7%) patients, although 281 (89%) adults and 99 (45%) children met criteria for vaccination.
Conclusions: Mortality in our population is similar to previous reports. More widespread pneumococcal vaccination in eligible populations may not only decrease mortality, but may also provide savings through decreased hospital admission and need for intensive care.
Key Words: bacteremia • Streptococcus pneumoniae • vaccination
Submitted on March 16, 1995
Accepted on July 29, 2007
This article has been cited by other articles:
|
|
 |
|
  C. Spindler and A. Ortqvist Prognostic score systems and community-acquired bacteraemic pneumococcal pneumonia Eur. Respir. J., October 1, 2006; 28(4): 816 - 823. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. P. W. Chan, J. G. H. Low, J. Raghuram, S. M. C. Fook-Chong, and A. Kurup Clinical Characteristics and Outcome of Severe Melioidosis Requiring Intensive Care Chest, November 1, 2005; 128(5): 3674 - 3678. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. R. Sherwood, C. Y. Lin, W. Tao, C. A. Hartmann, J. E. Dujon, A. J. French, and T. K. Varma {beta}2 Microglobulin Knockout Mice Are Resistant to Lethal Intraabdominal Sepsis Am. J. Respir. Crit. Care Med., June 15, 2003; 167(12): 1641 - 1649. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. S. Artz, W. B. Ershler, and D. L. Longo Pneumococcal Vaccination and Revaccination of Older Adults Clin. Microbiol. Rev., April 1, 2003; 16(2): 308 - 318. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. S. Watson, J. A. Carcillo, W. T. Linde-Zwirble, G. Clermont, J. Lidicker, and D. C. Angus The Epidemiology of Severe Sepsis in Children in the United States Am. J. Respir. Crit. Care Med., March 1, 2003; 167(5): 695 - 701. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Feldman, M. Glatthaar, R. Morar, A. G. Mahomed, S. Kaka, M. Cassel, and K. P. Klugman Bacteremic Pneumococcal Pneumonia in HIV-Seropositive and HIV-Seronegative Adults Chest, July 1, 1999; 116(1): 107 - 114. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
