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(Chest. 1996;109:1001-1005.)
© 1996 American College of Chest Physicians

Rates of Decline in Lung Function Among Subjects Who Restart Cigarette Smoking

Duane L. Sherrill PhD1; Paul Enright MD1; Martha Cline MS1; Benjamin Burrows MD1; and Michael D. Lebowitz PhD1

1 From the Respiratory Sciences Center, University of Arizona, College of Medicine, Tucson

Several studies have demonstrated that smokers who are able to break the habit generally experience reductions in respiratory symptoms and improvement in pulmonary function; however, far less attention has been given to smokers who are unsuccessful in their attempts at quitting. Recent reports have suggested that these subjects (restarters) may have steeper rates of decline in pulmonary function than subjects never attempting to quit smoking. In this study, we compared rates of decline in FEV1 between restarters and subjects who remained current, ex-smokers, or never-smokers throughout the observation period. The results showed that, in both sexes, subjects who attempt to quit the habit and then restart have significantly steeper rates of decline in their FEV1 than subjects who continue smoking uninterrupted. Female restarters also have significantly steeper rates of decline in FEV1 than ex-smokers. These effects were independent of the amount smoked and respiratory diseases.

Key Words: epidemiology • longitudinal • pulmonary function • smoking cessation

Submitted on July 7, 1995
Accepted on October 23, 2007




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