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(Chest. 1996;109:1370-1379.)
© 1996 American College of Chest Physicians

Bronchoprovocation Tests in the Diagnosis of Isocyanate-lnduced Asthma

Daniel E. Banks MD, FCCP1; Susan M. Tarlo MBBS, FCCP2; Fawzi Masri MS3; Roy J. Rando DSc4; and David N. Weissman MD, FCCP3

1 From the Section of Pulmonary and Critical Care Medicine, West Virginia University School of Medicine, Morgantown; and the Gage Research Institute, the University of Toronto, Toronto, Ontario, Canada
2 From the Gage Research Institute, the University of Toronto, Toronto, Ontario, Canada
3 From the Section of Pulmonary and Critical Care Medicine, West Virginia University School of Medicine, Morgantown
4 From the Department of Environmental Health Sciences, Tulane University School of Public Health, New Orleans

Over the past 25 years, investigators have continued to improve on the approach to providing nonirritant exposures for the accurate diagnosis of isocyanate-induced asthma. Although the technology used in testing has become more sophisticated and may be fairly considered the domain of the bioengineer, the chemist, and the industrial hygienist, the requirements of the physician have remained unchanged. The physician must observe the level of exposure closely and monitor the worker's symptoms and lung function. Direct physician involvement in the testing procedure remains critical to the worker's safety and for the accurate diagnosis of isocyanate-induced asthma.

Key Words: bronchoprovocation • diisocyanates • isocyanates • occupational asthma • toluene




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Am. J. Respir. Crit. Care Med.Home page
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Am. J. Respir. Crit. Care Med., August 1, 2005; 172(3): 280 - 305.
[Abstract] [Full Text] [PDF]




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Copyright © 1996 by the American College of Chest Physicians.