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(Chest. 1996;110:279-281.)
© 1996 American College of Chest Physicians

A Death Associated With Therapy for Nosocomially Acquired Multidrug-Resistant Tuberculosis

André C. Weltman MD, MSc1; George T. DiFerdinando Jr MD, MPH2; Rita Washko MD3; and William M. Lipsky MD4

1 From the Bureau of Tuberculosis Control, New York State Department of Health, Albany; the Epidemic Intelligence Service and Division of Field Epidemiology, Epidemiology Program Office, Centers for Disease Control and Prevention, Atlanta
2 From the Bureau of Tuberculosis Control, New York State Department of Health, Albany; the Department of Epidemiology, School of Public Health, State University of New York, Albany
3 From the Epidemic Intelligence Service and Division of Field Epidemiology, Epidemiology Program Office, Centers for Disease Control and Prevention, Atlanta; the Bureau of Tuberculosis Control, New York City Department of Health, New York
4 From the Whitestone, NY.

Treatment of multidrug-resistant tuberculosis is difficult and has been associated rarely with severe side effects. We report the nosocomial transmission of multidrug-resistant tuberculosis to a health-care worker who was seronegative for HIV infection. She died because of liver failure associated with treatment for active multidrug-resistant tuberculosis.

Key Words: adverse effect • drug resistance • therapy • tuberculosis

Submitted on August 8, 1995
Accepted on October 19, 2007







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