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(Chest. 1996;110:1416-1424.)
© 1996 American College of Chest Physicians

Spirometry Reference Values for Healthy Elderly Blacks

Paul L. Enright MD1; Alice Arnold PhD1; Teri A. Manolio MD1; Lewis H. Kuller MD1; and ;Cardiovascular Health Study Research Group1

1 From the University of Arizona Health Sciences Center, Tucson

Pulmonary function was assessed by spirometry in 497 black and 2,980 white ambulatory elderly male and female participants of the Cardiovascular Health Study. The quality assurance program prompted technicians to exceed American Thoracic Society recommendations for spirometry. A "healthy" subgroup of 235 black and 1,227 white participants age 65 years and older was identified by excluding current and former smokers, and those with self-reported asthma or emphysema, congestive heart failure, and poor-quality results of spirometry tests, since those factors were associated with a lower FEV1. Reference equations and normal ranges for elderly blacks for measurements of FEV1, FVC, and the FEV1/FVC ratio were then determined from the healthy group. These elderly blacks had an FVC about 6% lower than elderly whites, even after correcting for standing height, sitting height (trunk length), and age. The popular use of spirometry reference values from studies of middle-aged white subjects by applying a 12% race correction factor for black patients appears to overestimate predicted values.

Key Words: elderly • normative values • prediction equations • reference equations • spirometry

Submitted on February 6, 1996
Accepted on July 5, 2007




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