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(Chest. 1997;112:840-842.)
© 1997 American College of Chest Physicians

Pulmonary Embolism Presenting as Seizures

Joseph E. Marine MD1 and Samuel Z. Goldhaber MD, FCCP1

1 From the Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston

Two patients with massive pulmonary embolism (PE) presented with generalized seizures. Pathophysiologic abnormalities that explain this clinical syndrome include respiratory acidosis, hypoxemia, and cerebral hypoperfusion due to decreased cardiac output. PE should be considered in the differential diagnosis of new-onset and otherwise unexplained seizures.

Key Words: diagnosis • pulmonary embolism • seizures

Submitted on December 26, 1996
Accepted on March 2, 1997






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Copyright © 1997 by the American College of Chest Physicians.