Chest ACCP Member Benefits
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Guest Access | Sign In via User Name/Password
This Article
Right arrow Full Text (PDF) Free
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Article Archive
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Totapally, B. R.
Right arrow Articles by Walsh, W. T.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Totapally, B. R.
Right arrow Articles by Walsh, W. T.
(Chest. 1998;113:1207-1214.)
© 1998 American College of Chest Physicians

Pneumococcal Bacteremia in Childhood

A 6-Year Experience in a Community Hospital

Balagangadhar R. Totapally MD1 and William T. Walsh PhD1

1 From the Departments of Pediatrics and Pathology, Hurley Medical Center, Flint, Mich.

Objective: To review the clinical and laboratory findings in children with pneumococcal bacteremia during a 6-year period between 1989 and 1995.

Design: Retrospective review of medical records identified from computer-generated blood culture records.

Setting: Hurley Medical Center in Flint, Mich, a community teaching hospital affiliated with Michigan State University.

Measurements: Data concerning age, gender, race, clinical findings, laboratory features, nature of antibiotic therapy, source of bacteremia, and outcome were obtained from patient medical records.

Results: Most (68%) of the children with pneumococcal bacteremia were <2 years of age. About 50% of the cases of invasive pneumococcal disease in childhood occurred between February and May. Focal source of bacteremia was as follows: 11.5% had meningitis, 37% had pneumonia, 30% had otitis media, and 33% had no focal source. Overall, 60% of children were African-Americans, although in children with meningitis, whites were predominant (p<0.04). Leukocytosis was present in 81% and bandemia >1,500/µL was present in 53% of children. The overall mortality was 1.6% with a case fatality rate for meningitis of 14%. Penicillin resistance was found in 6.5% of pneumococcal isolates, although during 1 study year (1993), 17% of all pneumococcal isolates from all sources in the same hospital were found to be penicillin resistant.

Conclusions: Clinical and laboratory findings seen in children with pneumococcal bacteremia at a community hospital are presented with a review of literature. Pneumococci isolated from sterile body sites were found to be less resistant to antibiotics compared with those isolated from nonsterile body sites.

Key Words: antibiotic resistance • bacteremia • children • community hospital • Streptococcus pneumoniae

Submitted on June 24, 1997
Accepted on October 20, 1997




This article has been cited by other articles:


Home page
 ChestHome page
C. Feldman, M. Glatthaar, R. Morar, A. G. Mahomed, S. Kaka, M. Cassel, and K. P. Klugman
Bacteremic Pneumococcal Pneumonia in HIV-Seropositive and HIV-Seronegative Adults
Chest, July 1, 1999; 116(1): 107 - 114.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1998 by the American College of Chest Physicians.