| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
Guest Access | Sign In via User Name/Password
|
|
|
|||||||
Guest Access | Sign In via User Name/Password |
|||||||||
1 From the Department of Surgery, Creighton University Medical Center, Omaha, NE.
Walter J. Scott, MD, FCCP, Cardiothoracic Surgery Division, Department of Surgery, Creighton University Medical Center/Saint Joseph Hospital 601 N 30th St, Suite 3740, Omaha, NE 68131; email: wscott{at}creighton.edu
Objective: The purpose of this study is to examine the accuracy and complications of transthoracic needle aspiration biopsy (TTNA) to determine its optimal role in the evaluation of patients with lung tumors.
Materials and methods: The charts of 130 consecutive patients who had undergone CT-guided TTNA were reviewed retrospectively. Thirty-two (25%) of these patients had subsequent surgery and 5 had subsequent transbronchial biopsy (TBB). Using the final surgical and TBB diagnosis as a reference, the accuracy, sensitivity, specificity, and prevalence of malignancy were calculated. Each case was also examined to determine the presence or absence of complications.
Results: Of the 130 biopsy results, 95 (73%) were malignant, 33 (25%) were nonspecific, and only 2 (2%) had a specific benign diagnosis. Thirty-two patients subsequently underwent surgical resection. The overall prevalence of malignancy after surgical diagnosis was 91%. The overall diagnostic accuracy of TTNA was 76%. The sensitivity of TTNA for the detection of malignancy was 74% and its specificity was 100%. When comparing TTNA results of small (<3 cm) and large (
3 cm) tumors, the occurrence of nonspecific results was 36% and 16%, respectively. Fifty-six (43%) patients had a pneumothorax subsequent to TTNA. Twenty-four (43%) of these patients required a chest tube and remained hospitalized for a mean of 6 days.
Conclusion: Patients who are surgical candidates and have a high clinical suspicion for malignancy should undergo surgical biopsy and resection of their lung tumors if indicated. Information gained from TTNAs performed on this patient population will rarely result in a change in their clinical management.
Key Words: diagnosis • lung cancer • SPN • TTNA
Submitted on August 19, 1997
Accepted on March 2, 1998
This article has been cited by other articles:
|
|
 |
|
  G. Paone, E. Nicastri, G. Lucantoni, R. Dello Iacono, P. Battistoni, A. L. D'Angeli, and G. Galluccio Endobronchial Ultrasound-Driven Biopsy in the Diagnosis of Peripheral Lung Lesions Chest, November 1, 2005; 128(5): 3551 - 3557. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. K. Carlson, J. P. Felmlee, C. E. Bender, R. L. Ehman, K. L. Classic, T. L. Hoskin, W. S. Harmsen, and H. H. Hu CT Fluoroscopy-guided Biopsy of the Lung or Upper Abdomen with a Breath-hold Monitoring and Feedback System: A Prospective Randomized Controlled Clinical Trial Radiology, November 1, 2005; 237(2): 701 - 708. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. S. Chandan, K. Zimmerman, P. Baker, E. Scalzetti, and K. K. Khurana Usefulness of Core Roll Preparations in Immediate Assessment of Neoplastic Lung Lesions: Comparison to Conventional CT Scan-Guided Lung Fine-Needle Aspiration Cytology Chest, September 1, 2004; 126(3): 739 - 743. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Shinagawa, K. Yamazaki, Y. Onodera, K. Miyasaka, E. Kikuchi, H. Dosaka-Akita, and M. Nishimura CT-Guided Transbronchial Biopsy Using an Ultrathin Bronchoscope With Virtual Bronchoscopic Navigation Chest, March 1, 2004; 125(3): 1138 - 1143. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. R. Geraghty, S. T. Kee, G. McFarlane, M. K. Razavi, D. Y. Sze, and M. D. Dake CT-guided Transthoracic Needle Aspiration Biopsy of Pulmonary Nodules: Needle Size and Pneumothorax Rate Radiology, November 1, 2003; 229(2): 475 - 481. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A Manhire, M Charig, C Clelland, F Gleeson, R Miller, H Moss, K Pointon, C Richardson, and E Sawicka Guidelines for radiologically guided lung biopsy Thorax, November 1, 2003; 58(11): 920 - 936. [Full Text] [PDF]
|
|
|
|
 |
|
 Y. Lacasse, J. Plante, S. Martel, and B. Raby Transthoracic needle biopsy in the diagnosis of solitary pulmonary nodules: a survey of canadian physicians J. Thorac. Cardiovasc. Surg., September 1, 2003; 126(3): 761 - 768. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Schreiber and D. C. McCrory Performance Characteristics of Different Modalities for Diagnosis of Suspected Lung Cancer: Summary of Published Evidence Chest, January 1, 2003; 123(1_suppl): 115S - 128S. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Saji, H. Nakamura, T. Tsuchida, M. Tsuboi, N. Kawate, C. Konaka, and H. Kato The Incidence and the Risk of Pneumothorax and Chest Tube Placement After Percutaneous CT-Guided Lung Biopsy* : The Angle of the Needle Trajectory Is a Novel Predictor Chest, May 1, 2002; 121(5): 1521 - 1526. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J.F. Beamis, H.D. Becker, S. Cavaliere, H. Colt, J.P. Diaz-Jimenez, J.F. Dumon, E. Edell, K.L. Kovitz, H.N. Macha, A.C. Mehta, et al. ERS/ATS statement on interventional pulmonology: Chairmen: C.T. Bolliger, P.N. Mathur Eur. Respir. J., February 1, 2002; 19(2): 356 - 373. [Full Text] [PDF]
|
|
|
|
|
|
J.F. Vansteenkiste Imaging in lung cancer: positron emission tomography scan Eur. Respir. J., February 1, 2002; 19(35_suppl): 49S - 60s. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Sawabata, H. Maeda, M. Ohta, and M. Hayakawa Operable Non-small Cell Lung Cancer Diagnosed by Transpleural Techniques : Do They Affect Relapse and Prognosis? Chest, November 1, 2001; 120(5): 1595 - 1598. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J.F. Vansteenkiste and S.G. Stroobants The role of positron emission tomography with 18F-fluoro-2-deoxy-D-glucose in respiratory oncology Eur. Respir. J., April 1, 2001; 17(4): 802 - 820. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Sawabata, M. Ohta, and H. Maeda Fine-Needle Aspiration Cytologic Technique for Lung Cancer Has a High Potential of Malignant Cell Spread Through the Tract Chest, October 1, 2000; 118(4): 936 - 939. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. M. Rozenblit, J. Tuvia, G. N. Rozenblit, and A. Klink CT-Guided Transthoracic Needle Biopsy Using an Ipsilateral Dependent Position Am. J. Roentgenol., June 1, 2000; 174(6): 1759 - 1764. [Abstract] [Full Text]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
