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(Chest. 1998;114:965-968.)
© 1998 American College of Chest Physicians

Exercise Limitation in Obstructive Lung Disease

Cristina Murariu MD1; Herberto Ghezzo PhD2; Joseph Milic-Emili MD2; and Henry Gautier MD1

1 From the Service d'Explorations Fonctionnelles Respiratoires, Hôpital St. Antoine, Paris, France
2 From the Meakins-Christie Laboratories McGill University, Montreal, Canada

Cristina Murariu, MD, Lahoratoire de Physiologie Respiratoire, Faculté de Medecine St. Antoine, 27, rue Chaligny, 75012, Paris, France

Objective: To study the relationship of resting pulmonary function to maximal exercise power output (Wmax) in obstructive lung disease (OLD).

Setting: University Hospital Pulmonary Function Laboratory.

Subjects: Twenty-five patients with OLD (6 with asthma and 19 with COPD).

Methods: Measurement of pulmonary lung function, resting arterial blood gases, and maximal symptom-limited exercise on a cycle ergometer.

Results and conclusions: In OLD, the only significant contributor to Wmax was the inspiratory capacity (r2 = 0.66; p < 0.001).

Key Words: arterial PO2 • inspiratory capacity • maximal power output • routine lung function • spirometry

Submitted on September 25, 1997
Accepted on April 23, 1998




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