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1 From the Departments of Radiology, Medicine, and Pathology, School of Medicine, The Johns Hopkins Medical Institutions, Baltimore, MD.
Stephen Solomon, MD, Blalock 545, The Johns Hopkins Hospital, 600 North Wolfe St., Baltimore, MD 21287; e-mail: ssolomo{at}welchlink.welch.jhu.edu
Study objective: To determine the feasibility of using real-time bronchoscope position technology coupled with previously acquired three-dimensional CT data to enhance transbronchial needle aspiration (TBNA).
Design: Eight swine were given percutaneously created target lesions for TBNA. A miniature position sensor was placed at the tip of a bronchoscope, and real-time position information during bronchoscopy was presented on a monitor simultaneously displaying previously acquired three-dimensional CT data.
Interventions: TBNA of target lesions and submucosal ink-spot injection of computer-generated targets.
Measurements and results: TBNA specimens revealed successful aspiration of target material. Distances between ink marks made at computer-generated tracheal targets varied, on average (±SD), 4.2 mm ± 2.6 mm from predetermined computer-distance coordinates.
Conclusion: Real-time bronchoscope position technology coupled with previously acquired CT images may aid with TBNA of nonvisible extrabronchial lesions.
Key Words: animal model • biopsy • bronchoscopy • CT bronchoscopy • image-guided surgery • transbronchial needle aspiration • virtual bronchoscopy
Submitted on January 13, 1998
Accepted on June 22, 1998
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