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(Chest. 1998;114:1535-1537.)
© 1998 American College of Chest Physicians

Digital Clubbing and Lung Cancer

Kasi S. Sridhar MD, FCCP1; Christopher F. Lobo BA/BS1; and Roy D. Altman MD1

1 From the Divisions of Hematology/Oncology and Rheumatology, Department of Medicine, Sylvester Comprehensive Cancer Center, University of Miami School of Medicine, Miami, FL, and the Royal College of Surgeons, Dublin, Ireland

Kasi S. Sridhar, Professor of Medicine, University of Miami School of Medicine, 1475 N.W. 12 Avenue (D8-4), Miami, FL 33136

Objectives: To determine the relative frequency of clubbing in small cell lung carcinoma (SCLC) versus non-small cell lung carcinoma (NSCLC).

Design: Examine patients with lung cancer for digital clubbing and relate the findings to the histopathologic subtype of lung cancer.

Setting: Cancer center at a tertiary teaching hospital.

Patients or Participants: One hundred and eleven consecutive patients with a pathological diagnosis of lung cancer examined by one physician (KSS).

Interventions: None.

Measurements and Results: Clubbing was present in 32 (29%) of the 111 patients with lung cancer. Clubbing was more common in women (40%) than in men (19%; khgr2 test p = 0.011), and was more common in patients with NSCLC (35%) than those with SCLC (4%; khgr2 test p = 0.0036).

Conclusion: In a prospective study, digital clubbing was less frequently observed in men than women and in patients with SCLC than NSCLC. These clinical observations may assist in the initial evaluation of patients for planning workup and therapy.

Key Words: clubbing • diagnosis of lung cancer • lung cancer

Submitted on September 16, 1997
Accepted on August 4, 1998




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