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(Chest. 1999;115:1740-1742.)
© 1999 American College of Chest Physicians

Pulmonary Manifestations of POEMS Syndrome*

Case Report and Literature Review

Babak Mokhlesi , MD and Manu Jain , MD

* From the Division of Pulmonary and Critical Care, Department of Medicine, Northwestern University Medical School, Chicago, IL.

Phrenic nerve paresis is an unusual complication of POEMS (polyneuropathy, organomegaly, endocrinopathy, M-protein spike and skin changes) syndrome. In this report, we describe a case of POEMS syndrome in which a 56-year-old woman presented with dyspnea and ventilatory failure due to bilateral phrenic nerve paralysis. To our knowledge, only one other case of phrenic neuropathy in POEMS syndrome has been reported.

Key Words: diaphragm • multiple myeloma • neuropathy • paralysis • phrenic • POEMS syndrome • pulmonary • respiratory failure




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