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(Chest. 1999;116:231-233.)
© 1999 American College of Chest Physicians

Small Airways Obstruction Syndrome*

Dan Stanescu, MD, PhD

* From the Pulmonary Laboratory and Division, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium.

Correspondence to: Dan Stanescu, MD, PhD, Cliniques Universitaires Saint-Luc, Avenue Hippocrate 10, 1200 Bruxelles, Belgium; e-mail: Stanescu{at}pneu.ucl.ac.be

Study objectives: To clarify the significance of a functional lung pattern characterized by a decreased vital capacity (VC) and an increased residual volume (RV), but with a normal FEV1/VC ratio.

Setting: A university teaching hospital.

Subjects: Patients with bronchial asthma, pulmonary emphysema, and small airways disease, and older subjects.

Measurements: Measurements of static and dynamic lung volumes, diffusing capacity of the lung for carbon monoxide (as measured by the single-breath method), nitrogen slope of the alveolar plateau, and closing volume (as measured by the single-breath O2 test).

Conclusion: A functional pattern characterized by a decreased VC and FEV1 and increased RV, but with a normal FEV1/VC ratio and total lung capacity, reflects an obstructive impairment of small airways.

Key Words: bronchial asthma • FEV1 • obstructive syndrome • pulmonary emphysema • residual volume • small airways • spirometry




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eLetters:

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Small Airway Obstruction or restrictive ventilatory impairment
Mehmet POLATLI
Chest Online, 9 Dec 1999 [Full text]

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