Chest ACCP Member Benefits
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Guest Access | Sign In via User Name/Password
This Article
Right arrow Full Text Free
Right arrow Full Text (PDF) Free
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Article Archive
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via ISI Web of Science (6)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Kano, H.
Right arrow Articles by Hiroe, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kano, H.
Right arrow Articles by Hiroe, M.
(Chest. 1999;116:868-873.)
© 1999 American College of Chest Physicians

Mechanism of Overshoot in Cardiac Function During Recovery From Submaximal Exercise in Man*

Hiroshi Kano, MD; Akira Koike, MD; Takashi Yajima, MD; Yoshiharu Koyama, MD; Fumiaki Marumo, MD and Michiaki Hiroe, MD

* From the Second Department of Internal Medicine (Drs. Kano, Yajima, Koyama, Marumo, and Hiroe), and the Department of Critical Care Medicine (Dr. Koike), Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan.

Correspondence to: Akira Koike, MD, Department of Critical Care Medicine, Tokyo Medical and Dental University, 5–45 Yushima 1-chome, Bunkyo-ku, Tokyo 113-8519, Japan

Background: A sudden increase (overshoot) in the left ventricular ejection fraction during the recovery from maximal exercise has been reported in patients with coronary artery disease, but its mechanism has not been fully clarified. We investigated whether this phenomenon may occur in normal subjects, and whether it depends on the intensity of exercise.

Methods: Thirteen normal subjects (mean [± SD] age, 59 ± 8 years old) performed two levels (25 W and 50 W) of mild-intensity, constant-work-rate exercise for 6 min on a cycle ergometer. Left ventricular function was monitored continuously during the recovery from exercise using a computerized cadmium telluride detector.

Results: An overshoot was observed in the ejection fraction during the first minute of recovery compared with the end-exercise value. The overshoot in the ejection fraction during recovery after the 50-W exercise was greater than that seen after the 25-W exercise. An overshoot phenomenon in stroke volume was also observed during the recovery from 50-W exercise.

Conclusions: The overshoot in cardiac function observed during the early phase of recovery, which was caused mainly by an immediate decrease in end-systolic volume, occurred even after exercise of mild intensity. This phenomenon appears to suggest the existence of a transient mismatch between cardiac contractility and afterload reduction during the recovery from mild-intensity exercise, even in normal subjects.

Key Words: ejection fraction • mild-intensity exercise • overshoot phenomenon • stroke volume




This article has been cited by other articles:


Home page
 RadiologyHome page
A. A. W. Roest, A. de Roos, H. J. Lamb, W. A. Helbing, J. G. van den Aardweg, J. Doornbos, E. E. van der Wall, and P. Kunz
Tetralogy of Fallot: Postoperative Delayed Recovery of Left Ventricular Stroke Volume after Physical Exercise--Assessment with Fast MR Imaging
Radiology, January 1, 2003; 226(1): 278 - 284.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1999 by the American College of Chest Physicians.