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* From the Departments of Medicine (Drs. Ip, Lam, Tsang, and Lam, and Ms. Mok), Statistics and Actuarial Science (Dr. Lauder), and Psychiatry (Dr. Chung), The University of Hong Kong, Hong Kong, SAR, China.
Correspondence to: Mary S. M. Ip, MD, FCCP, Department of Medicine, The University of Hong Kong, 4/F, Professorial Block, Queen Mary Hospital, Pokfulam Rd, Hong Kong SAR, China; e-mail: msmip{at}hkucc.hku.hk
Background: Sleep-disordered breathing (SDB) in Asian populations is being increasingly recognized. This study investigated the prevalence of SDB in Chinese middle-aged office-based male workers in Hong Kong.
Methods: Sleep questionnaires were
distributed to 1,542 men (age range, 30 to 60 years), and 784
questionnaires were returned. Subsequently, full polysomnographic (PSG)
examinations were conducted in 153 questionnaire respondents. Subjects
with an apnea-hypopnea index (AHI)
5 were recalled for clinical
assessment.
Results: Questionnaire respondents were
similar in age and body mass index (BMI) to the general community in
the target age range and gender. Habitual snoring was reported by 23%
of this cohort and was associated with excessive daytime sleepiness
(EDS), hypertension, witnessed abnormal breathing pattern, BMI, and leg
movements during sleep. Allowing for subject bias in undergoing PSG,
the estimated prevalence of SDB and obstructive sleep apnea syndrome
(OSAS) (defined as SDB in the presence of EDS) at various AHI cutoff
threshold values was 8.8% and 4.1% (AHI
5), 6.3% and 3.2% (AHI
10), and 5.3% and 3.1% (AHI
15). Multiple stepwise logistic
regression analysis identified BMI, habitual snoring, time taken to
fall asleep, and age as predictors of SDB at AHI
5. Analysis of
anthropometric parameters indicated that the relative risk of OSAS
attributable to obesity was less than in white subjects.
Conclusion: This community-based study of sleep apnea among
middle-aged men in Hong Kong using full PSG demonstrated an estimated
prevalence of OSAS (AHI
5 and EDS) at 4.1%. Increasing BMI and age
were associated with SDB, although factors other than adiposity may
also have an important pathogenic role in OSA in Chinese
subjects.
Key Words: middle-aged Chinese men polysomnography sleep apnea
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