Chest Email Content Delivery
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Guest Access | Sign In via User Name/Password
This Article
Right arrow Full Text Free
Right arrow Full Text (PDF) Free
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Article Archive
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by San Pedro, G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by San Pedro, G.
(Chest. 2001;119:385S-390S.)
© 2001 American College of Chest Physicians

Are Quantitative Cultures Useful in the Diagnosis of Hospital-Acquired Pneumonia?*

Gerry San Pedro, MD

* From the Department of Internal Medicine, Section of Pulmonary and Critical Care Medicine, Louisiana State University Health Sciences Center at Shreveport, Shreveport, LA.

Correspondence to: Gerry San Pedro, MD, Section of Pulmonary and Critical Care Medicine, Louisiana State University Health Sciences Center at Shreveport, 1501 Kings Highway, PO Box 33932, Shreveport, LA 71130-3932; e-mail: gerrsp{at}prysm.net

Noninvasive and invasive tests have been developed and studied for their utility in diagnosing and guiding the treatment of hospital-acquired pneumonia, a condition with an inherently high mortality. Early empiric antibiotic treatment has been shown to reduce mortality, so delaying this treatment until test results are available is not justifiable. Furthermore, tailoring therapy based on results of either noninvasive or invasive tests has not been clearly shown to affect morbidity and mortality. This may be related to quantitative limitations of these tests or possibly to a high false-negative rate in patients who receive early antibiotic treatment and may therefore have suppressed bacterial counts. Results of these tests, however, do influence treatment. It is therefore hoped that they may ultimately provide a rational basis for making therapeutic decisions. In the future, outcomes research should be a part of large-scale clinical trials, and noninvasive and invasive tests should be incorporated into the design in an attempt to provide a better understanding of the value of such tests.

Key Words: bacteriology • BAL • bronchoscopy • diagnosis • endotracheal aspiration • hospital-acquired pneumonia






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2001 by the American College of Chest Physicians.