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(Chest. 2001;119:1280-1282.)
© 2001 American College of Chest Physicians

Continuous Calcium Chloride Infusion for Massive Nifedipine Overdose*

Yui-Ming Lam, MB; Hung-Fat Tse, MD and Chu-Pak Lau, MD, FCCP

* From the Division of Cardiology, Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, China.

Correspondence to: Hung-Fat Tse, MD, Division of Cardiology, Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, China; e-mail: hftse{at}hkucc.hku.hk

A 37-year-old woman presented with persistent hypotension and noncardiogenic pulmonary edema after massive nifedipine overdose. Judicious use of continuous and prolonged high-dose IV calcium infusion was administered to provide sustained increases in serum ionic calcium level (approximately 2 mmol/L) and was able to improve the hemodynamic status without any major adverse reaction.

Key Words: calcium chloride infusion • nifedipine overdose




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