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* From the Pulmonary Division (Drs. Bloch, Boehler, and Russi), and Thoracic Surgery Division (Dr. Weder), and Department of Anesthesiology (Dr. Zalunardo), University Hospital of Zürich, Switzerland.
Correspondence to: Konrad E. Bloch, MD, FCCP, Pulmonary Division, Department of Internal Medicine, University Hospital of Zürich, Rämistrasse 100, CH-8091 Zürich, Switzerland; e-mail: pneubloc{at}usz.unizh.ch
Lung volume reduction surgery (LVRS) may improve pulmonary function in patients with severe emphysema. However, its effects in other types of obstructive lung disease are unknown. To delay the need for lung transplantation, we performed LVRS in a 14-year-old boy with disabling airflow obstruction/hyperinflation secondary to postinfectious bronchiolitis nonresponsive to medical therapy. Within days after LVRS, a major improvement of symptoms and lung function occurred and persisted for > 1 year. Our observation suggests that LVRS may be a novel treatment option in selected patients with extreme hyperinflation even if the underlying disease is not emphysema.
Key Words: bronchiolitis emphysema lung volume reduction surgery obstructive lung disease surgery video-assisted surgery
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