HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:
Guest Access | Sign In via User Name/Password

This Article Full Text Free Full Text (PDF) Free Submit a response Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in ISI Web of Science Similar articles in PubMed Alert me to new issues of the journal Add to My Personal Article Archive Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via ISI Web of Science (19) Citing Articles via Google Scholar Google Scholar Articles by Chan, S. L. Articles by Tsang, K. W. Search for Related Content PubMed PubMed Citation Articles by Chan, S. L. Articles by Tsang, K. W.

Validation of the Hong Kong Chinese Version of the St. George Respiratory Questionnaire in Patients With Bronchiectasis^*

^* From the Departments of Medicine (Ms. Chan and Drs. Chan-Yeung, C.L. Lam, W.K. Lam, and Tsang), Diagnostic Radiology (Dr. Ooi), and School of Professional and Continued Education (Dr. Cheung), The University of Hong Kong, Hong Kong, Special Administrative Region.

Correspondence to: Kenneth W. Tsang, MD, FCCP, Associate Professor and Honorary Consultant Physician, University Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Pokfulam, Hong Kong, Special Administrative Region; e-mail: kwttsang{at}hku.hk

Study objectives: To validate the Hong Kong Chinese version of the St. George Respiratory Questionnaire (SGRQ-HK) in patients with bronchiectasis.

Design and setting: Outpatients (93 patients; 61 women; mean age [± SD], 59.0 ± 14.2 years) were assessed at baseline by the SGRQ-HK, the Hong Kong Chinese version of the 36-item short form health survey (SF-36-HK), and the hospital anxiety and depression scale (HADS). Forty randomly selected patients also were reassessed at 2 weeks for repeatability. Seventy-two patients were further reassessed at 6 months for responsiveness.

Measurements and results: Cronbach coefficients, which reflected internal consistency, were > 0.7 for all SGRQ-HK components except for symptoms ( = 0.59), and the intraclass correlation coefficients between baseline and the 2-week follow-up visits were between 0.80 and 0.94 (p > 0.05). SGRQ-HK component scores and total scores correlated with all the component scores of the SF-36-HK and the HADS (p < 0.02). SGRQ-HK component scores and total scores correlated with the scores of the SF-36-HK and the HADS, confirming the concurrent validity. All SGRQ-HK scores correlated negatively with FEV₁, FVC, and arterial oxygen saturation (p < 0.005), while the activity score correlated with the Karnofsky performance scale and the number of bronchiectatic lobes (p < 0.001). SGRQ-HK scores positively correlated with Borg scale scores, exacerbation frequency, and 24-h sputum volumes (p < 0.03). Patients with 24-h sputum volumes of 10 mL or < 10 mL had significantly different SQRG-HK component scores and total scores (p < 0.002), although this sensitivity was not displayed by scores on the HADS or the SF-36-HK. Patients with 25% reductions in 24-h sputum volumes had significant improvements in SGRQ-HK activity scores, impact scores, and total scores (p < 0.02), but not in other quality-of-life measures or clinical parameters, indicating the responsiveness of the SGRQ-HK.

Conclusion: The SGRQ-HK is a valid and sensitive instrument for determining quality of life in bronchiectasis patients.

Key Words: bronchiectasis • hospital anxious and depression scale • MOS short form-36 • quality of life • St. George Respiratory Questionnaire

This article has been cited by other articles:

				J. G. Pasipanodya, T. L. Miller, M. Vecino, G. Munguia, S. Bae, G. Drewyer, and S. E. Weis Using the St. George Respiratory Questionnaire To Ascertain Health Quality in Persons With Treated Pulmonary Tuberculosis Chest, November 1, 2007; 132(5): 1591 - 1598. [Abstract] [Full Text] [PDF]

				T.-P. Ng, M. Niti, W.-C. Tan, Z. Cao, K.-C. Ong, and P. Eng Depressive Symptoms and Chronic Obstructive Pulmonary Disease: Effect on Mortality, Hospital Readmission, Symptom Burden, Functional Status, and Quality of Life Arch Intern Med, January 8, 2007; 167(1): 60 - 67. [Abstract] [Full Text] [PDF]

				M. A. Martinez-Garcia, M. Perpina-Tordera, P. Roman-Sanchez, and J. J. Soler-Cataluna Quality-of-Life Determinants in Patients With Clinically Stable Bronchiectasis Chest, August 1, 2005; 128(2): 739 - 745. [Abstract] [Full Text] [PDF]

				K W Tsang, K C Tan, P L Ho, G C Ooi, J C Ho, J Mak, G L Tipoe, C Ko, C Yan, W K Lam, et al. Inhaled fluticasone in bronchiectasis: a 12 month study Thorax, March 1, 2005; 60(3): 239 - 243. [Abstract] [Full Text] [PDF]

				A. P. C. Yim, T. M. T. Hwong, T. W. Lee, W. W. L. Li, S. Lam, T. K. Yeung, D. S. C. Hui, F. W. S. Ko, A. D. L. Sihoe, K. H. Thung, et al. Early results of endoscopic lung volume reduction for emphysema J. Thorac. Cardiovasc. Surg., June 1, 2004; 127(6): 1564 - 1573. [Abstract] [Full Text] [PDF]