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(Chest. 2003;123:202S-220S.)
© 2003 American College of Chest Physicians

Treatment of Stage IIIA Non-small Cell Lung Cancer*

Lary A. Robinson, MD, FCCP; Henry Wagner, Jr., MD and John C. Ruckdeschel, MD, FCCP

* From the Thoracic Oncology Program, Department of Interdisciplinary Oncology, H. Lee Moffitt Cancer Center and Research Institute, University of South Florida, Tampa, FL.

Correspondence to: Lary A. Robinson, MD, FCCP, Division of Cardiovascular and Thoracic Surgery, Thoracic Oncology Program, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Dr, Tampa, FL 33612-9497; e-mail: robinson{at}moffitt.usf.edu

Stage IIIA non-small cell lung cancer represents a relatively heterogeneous group of patients with metastatic disease to the ipsilateral mediastinal (N2) lymph nodes and also includes T3N1 patients. Presentations of disease range from apparently resectable tumors with occult microscopic nodal metastases to unresectable, bulky multistation nodal disease. Controversy abounds as to the optimal treatment of the various stage IIIA subsets, which is fueled by a lack of meaningful, large randomized trials. Multimodality therapy of some type appears to be preferable in stage IIIA patients.

Key Words: adjuvant chemotherapy • adjuvant radiotherapy • chemotherapy • guidelines • lung carcinoma • neoadjuvant therapy • non-small cell lung cancer • pulmonary surgical procedures • radiation therapy




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[Abstract] [Full Text] [PDF]


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