| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
Guest Access | Sign In via User Name/Password
|
|
|
|||||||
Guest Access | Sign In via User Name/Password |
|||||||||
* From the Department of Interdisciplinary Endoscopy (Drs. Herth and Becker), Thoraxklinik, Heidelberg, Germany; and Division of Pulmonary and Critical Care (Dr. Ernst), Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.
Correspondence to: Armin Ernst, MD, FCCP, Director, Interventional Pulmonology, Pulmonary and Critical Care Division, Beth Israel Deaconess Medical Center, Harvard Medical School, One Deaconess Rd, Boston, MA 02115; e-mail: aernst{at}caregroup.harvard.edu
Study objectives: Conventional transbronchial needle aspiration (TBNA) is a valuable procedure but remains underutilized. Recently, imaging guidance such as CT fluoroscopy has created considerable interest. As CT fluoroscopy is cumbersome and exposes patients and staff to radiation, we have examined the feasibility of endobronchial ultrasound (EBUS) in providing imaging support for TBNA.
Design: Prospective consecutive patient enrollment.
Setting: University-related tertiary referral centers for pulmonary diseases.
Results: From January 1999 to January 2000, 242 consecutive patients were entered into this prospective study (82 women and 160 men; mean age, 60.0 years). Indications for TBNA were diagnosis of enlarged lymph nodes and cancer staging. The average lymph node size was 1.7 cm (SD, 0.47; range, 0.8 to 4.3 cm). Target lymph nodes were visualized with EBUS, followed by TBNA in standard fashion. All targets could be visualized with EBUS. In 207 patients, the lymph nodes were successfully sampled (86%). This was independent of lymph node size and location. A firm diagnosis or cancer stage could be obtained in 172 patients (72%). There were no complications associated with the use of EBUS.
Conclusion: EBUS is simply performed and if used for TBNA guidance affords an excellent yield independent of lymph node location. Randomized trials comparing standard TBNA and imaging-guided TBNA by CT fluoroscopy and EBUS are indicated.
Key Words: bronchoscopy • diagnosis • endobronchial ultrasound • transbronchial needle aspiration
This article has been cited by other articles:
|
|
 |
|
  F. D. Sheski and P. N. Mathur Endobronchial Ultrasound Chest, January 1, 2008; 133(1): 264 - 270. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. J. F. Herth, A. Ernst, R. Eberhardt, P. Vilmann, H. Dienemann, and M. Krasnik Endobronchial ultrasound-guided transbronchial needle aspiration of lymph nodes in the radiologically normal mediastinum Eur. Respir. J., November 1, 2006; 28(5): 910 - 914. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. Feller-Kopman, W. Lunn, and A. Ernst Autofluorescence Bronchoscopy and Endobronchial Ultrasound: A Practical Review Ann. Thorac. Surg., December 1, 2005; 80(6): 2395 - 2401. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Paone, E. Nicastri, G. Lucantoni, R. Dello Iacono, P. Battistoni, A. L. D'Angeli, and G. Galluccio Endobronchial Ultrasound-Driven Biopsy in the Diagnosis of Peripheral Lung Lesions Chest, November 1, 2005; 128(5): 3551 - 3557. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S Gasparini and G A Silvestri Usefulness of transbronchial needle aspiration in evaluating patients with lung cancer Thorax, November 1, 2005; 60(11): 890 - 891. [Full Text] [PDF]
|
|
|
|
|
|
K. Kanoh, T. Miyazawa, N. Kurimoto, Y. Iwamoto, Y. Miyazu, and N. Kohno Endobronchial Ultrasonography Guidance for Transbronchial Needle Aspiration Using a Double-Channel Bronchoscope Chest, July 1, 2005; 128(1): 388 - 393. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. J. F. Herth, W. Lunn, R. Eberhardt, H. D. Becker, and A. Ernst Transbronchial versus Transesophageal Ultrasound-guided Aspiration of Enlarged Mediastinal Lymph Nodes Am. J. Respir. Crit. Care Med., May 15, 2005; 171(10): 1164 - 1167. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. C. Rintoul, K. M. Skwarski, J. T. Murchison, W. A. Wallace, W. S. Walker, and I. D. Penman Endobronchial and endoscopic ultrasound-guided real-time fine-needle aspiration for mediastinal staging Eur. Respir. J., March 1, 2005; 25(3): 416 - 421. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Yasufuku, M. Chiyo, Y. Sekine, P. N. Chhajed, K. Shibuya, T. Iizasa, and T. Fujisawa Real-time Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration of Mediastinal and Hilar Lymph Nodes Chest, July 1, 2004; 126(1): 122 - 128. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. Herth, H. D. Becker, and A. Ernst Conventional vs Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration: A Randomized Trial Chest, January 1, 2004; 125(1): 322 - 325. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. P. Massion and D. P. Carbone From Clinical and Pathologic to Molecular Staging of Lung Cancer Am. J. Respir. Crit. Care Med., June 15, 2003; 167(12): 1587 - 1588. [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
