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High Relapse-Free Survival After Preoperative and Intraoperative Radiotherapy and Resection for Sulcus Superior Tumors^*

Albertus N. van Geel, MD, PhD; Peter P. Jansen, MD; Rob J. van Klaveren, MD, PhD and Joost R. M. van der Sijp, MD, PhD; on behalf of the Rotterdam Oncological Thorax Study Group

^* From the Departments of Surgical Oncology (Drs. van Geel and van der Sijp), Radiotherapy (Dr. Jansen), and Pulmonary-Oncology (Dr. van Klaveren), Erasmus Medical Center/Daniel den Hoed, Rotterdam, the Netherlands. Dr. van der Sijp is currently at the Department of Surgical Oncology, VU Medical Center, Amsterdam, the Netherlands.

Correspondence to: A. N. van Geel, MD, PhD, Department of Surgical Oncology, Erasmus Medical Center/Daniel den Hoed, Groene Hilledijk 301, 3075 EA Rotterdam, the Netherlands; e-mail: geel{at}chih.azr.nl

Study objectives: Relapse-free survival in patients with sulcus superior tumors.

Design: Prospective registration study.

Setting: Department of surgical oncology of a university hospital.

Patients: Twenty-one patients treated with preoperative radiotherapy (46 Gy), lobectomy and chest-wall resection, and intraoperative radiotherapy (10 Gy).

Results: After a median follow-up of 18 months, 18 patients (85%) were free from locoregional relapse, while 8 patients were still alive.

Conclusions: The results show that this protocol can achieve excellent local tumor control and can even be used for palliative treatment.

Key Words: brachytherapy • chest wall resection • external beam radiotherapy • lung cancer • sulcus superior tumor

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