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Common Causes of Troponin Elevations in the Absence of Acute Myocardial Infarction^*

Incidence and Clinical Significance

^* From the Cardiovascular Division, Department of Internal Medicine (Dr. Roongsritong), and Department of Pathology (Drs. Warraich and Bradley), Texas Tech University Health Sciences Center, Lubbock, TX.

Correspondence to: Chanwit Roongsritong, MD, Department of Internal Medicine, Texas Tech University Health Sciences Center, 3601 Fourth St, Lubbock, TX 79430

Cardiac troponin is a preferred biomarker of acute myocardial infarction (MI). Unfortunately, elevation of troponin can be detected in a variety of conditions other than acute MI. This review focuses on the incidence and clinical significance of increased troponin in conditions commonly associated with troponin elevations, particularly in those that may resemble acute MI.

Key Words: false-positive • heart failure • pericarditis • pulmonary embolism • sepsis • troponin

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