Chest ACCP Member Benefits
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Guest Access | Sign In via User Name/Password
This Article
Right arrow Full Text Free
Right arrow Full Text (PDF) Free
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Article Archive
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via ISI Web of Science (17)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Kiljander, T. O.
Right arrow Articles by Laitinen, J. O.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kiljander, T. O.
Right arrow Articles by Laitinen, J. O.
(Chest. 2004;126:1490-1494.)
© 2004 American College of Chest Physicians

The Prevalence of Gastroesophageal Reflux Disease in Adult Asthmatics*

Toni O. Kiljander, MD, PhD and Jukka O. Laitinen, MD, PhD

* From the Departments of Pulmonary Diseases (Dr. Kiljander) and Clinical Physiology (Dr. Laitinen), Tampere University Hospital, Tampere, Finland.

Correspondence to: Toni Kiljander, MD, PhD, Department of Pulmonary Diseases, Tampere University Hospital, PO Box 2000, FIN-33521 Tampere, Finland; e-mail: toni.kiljander{at}fimnet.fi

Background: Asthma and gastroesophageal reflux disease (GERD) often coexist. However, the results of the studies investigating the prevalence of GERD among patients with asthma vary greatly.

Study objective: To investigate the prevalence of GERD in adult patients with asthma.

Subjects and methods: The basic study population consisted of 2,225 asthmatic patients who were treated in six specialist-headed hospitals during 1 year. From the common computer-based discharge register, every 14th patient was randomly selected for the study. Ninety of the 149 contacted patients (60%) agreed to participate in the study. Twenty-four–hour esophageal pH monitoring was performed on all patients.

Results: GERD was found in 32 of the patients (36%). Eight of these patients (25%) were free from classical reflux symptoms. Forty-seven of the 90 patients (52%) presented with typical reflux symptoms. Twenty-four of these patients (51%) were found to have abnormal acidic reflux.

Conclusions: According to the current study, one third of adult patients with asthma have GERD. These patients often do not have typical reflux symptoms. However, the presence of typical reflux symptoms in an asthmatic patient does not seem to guarantee the presence of abnormal acidic reflux.

Key Words: asthma • gastroesophageal reflux disease • prevalence




This article has been cited by other articles:


Home page
 ChestHome page
W.-J. Koh, J. H. Lee, Y. S. Kwon, K. S. Lee, G. Y. Suh, M. P. Chung, H. Kim, and O. J. Kwon
Prevalence of Gastroesophageal Reflux Disease in Patients With Nontuberculous Mycobacterial Lung Disease
Chest, June 1, 2007; 131(6): 1825 - 1830.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
A. L. Friedlander and M. B. Fessler
A 70-year-old man with migratory pulmonary infiltrates.
Chest, October 1, 2006; 130(4): 1269 - 1274.
[Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
T. O. Kiljander, S. M. Harding, S. K. Field, M. R. Stein, H. S. Nelson, J. Ekelund, M. Illueca, O. Beckman, and M. B. Sostek
Effects of Esomeprazole 40 mg Twice Daily on Asthma: A Randomized Placebo-controlled Trial
Am. J. Respir. Crit. Care Med., May 15, 2006; 173(10): 1091 - 1097.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2004 by the American College of Chest Physicians.