Chest ACCP Member Benefits
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Guest Access | Sign In via User Name/Password
This Article
Right arrow Full Text Free
Right arrow Full Text (PDF) Free
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Article Archive
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via ISI Web of Science (14)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Pépin, J.-L.
Right arrow Articles by Levy, P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Pépin, J.-L.
Right arrow Articles by Levy, P.
(Chest. 2005;127:722-730.)
© 2005 American College of Chest Physicians

Pulse Transit Time Improves Detection of Sleep Respiratory Events and Microarousals in Children*

Jean-Louis Pépin, MD, PhD; Nadège Delavie, MD; Isabelle Pin, MD; Chrystèle Deschaux, MSc; Jérôme Argod, PhD; Michel Bost, MD and Patrick Levy, MD, PhD

* From the Departments of Pediatrics and Respiratory Medicine, Intensive Care Unit and Sleep Laboratory, HP2 Laboratory EA3945 (Hypoxia: PhysioPathology), University Hospital, Grenoble, France.

Correspondence to: Jean-Louis Pépin, MD, PhD, Département de Médecine Aigue Spécialisée (DMAS), Unité Sommeil et Respiration, CHU de Grenoble, BP 217 X, 38043, Grenoble, France; e-mail: JPepin{at}chu-grenoble.fr

Objectives: To evaluate the additional information provided by pulse transit time (PTT), a noninvasive tool, when using during polysomnography for the diagnosis of sleep breathing disorders in a pediatric population.

Main findings: Respiratory and microarousals events were scored twice. The first scoring was performed using nasal pressure, thermistors, thoracic and abdominal movements, and oxygen saturation. The second scoring, blinded to the first scoring, was performed using PTT in combination with all the other signals. Microarousals were scored once visually on the EEG trace (cortical arousals [CAs]) and once using the PTT signal (autonomic arousals [AAs]) blinded to EEG. For the whole group of 16 children studied (mean age, 9.5 years), there was no significant difference between the respiratory disturbance index (RDI) with or without PTT analysis (22.4 ± 13.5/h vs 20.4 ± 14.3/h; not significant [mean ± SD]). Among the children exhibiting a "without PTT" RDI < 30/h, 5 of 12 children (41.66%) showed a clinically significant ≥ 5/h increase in RDI when using PTT. AAs detected by PTT were significantly more frequent than CAs during rapid eye movement (REM) sleep (7.4 ± 3.9/h vs 3.2 ± 2.3/h; p < 0.001) and slow wave sleep (SWS) [6.0 ± 4.3/h vs 0.6 ± 0.5/h; p < 0.0001].

Conclusions: The quantification of respiratory effort using PTT improves the detection of respiratory events in children. The detection of microarousals is improved particularly in REM and SWS.

Key Words: children • microarousal • nasal pressure • pulse transit time • sleep apnea




This article has been cited by other articles:


Home page
 ChestHome page
A. C. Halbower, S. L. Ishman, and B. M. McGinley
Childhood Obstructive Sleep-Disordered Breathing: A Clinical Update and Discussion of Technological Innovations and Challenges
Chest, December 1, 2007; 132(6): 2030 - 2041.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2005 by the American College of Chest Physicians.