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(Chest. 2005;128:3074-3075.)
© 2005 American College of Chest Physicians

Spontaneous Pneumothorax in Wegener Granulomatosis*

Isabelle Delèvaux, MD; Mehdi Khellaf, MD; Marc André, MD; Jean-Luc Michel, MD; Jean Charles Piette, MD and Olivier Aumaître, MD

* From the Department of Internal Medicine (Drs. Delèvaux, André, and Aumaître) and Department of Radiology (Dr. Michel), CHU de Clermont-Ferrand, Hôpital G. Montpied, Clermont-Ferrand; Department of Internal Medicine (Dr. Khellaf), Hôpital Henri Mondor, Créteil; and Department of Internal Medicine (Dr. Piette), CHU Pitié-Salpétrière, Paris, France.

Correspondence to: Isabelle Delèvaux, MD, Service de Médecine Interne, CHU Clermont-Ferrand, Hôpital G Montpied, 58 rue Montalembert, 63003 Clermont-Ferrand France; e-mail:idelevaux{at}chu-clermontferrand.fr

Spontaneous pneumothorax in Wegener granulomatosis (WG) is uncommon. Three cases of pneumothorax that occurred early in the course of this vasculitis are reported. In the first patient, the disorder was disclosed by a pyopneumothorax. In the second patient, a rupture of the subpleural cavitary nodule into the pleural space was observed. In the third patient, the pneumothorax was discovered at the same time as a pulmonary hemorrhage. The three patients improved with immunosuppressive therapy. In WG, the pulmonary nodules are predominantly in the subpleural location, which entails the risk of pneumothorax and therefore require particular attention.

Key Words: pyopneumothorax • spontaneous pneumothorax • vasculitis • Wegener granulomatosis






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