Chest ACCP Member Benefits
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Guest Access | Sign In via User Name/Password
This Article
Right arrow Full Text Free
Right arrow Full Text (PDF) Free
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Article Archive
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Strieter, R. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Strieter, R. M.
(Chest. 2005;128:526S-532S.)
© 2005 American College of Chest Physicians

Pathogenesis and Natural History of Usual Interstitial Pneumonia*

The Whole Story or the Last Chapter of a Long Novel

Robert M. Strieter, MD, FCCP

* From the Division of Pulmonary and Critical Care Medicine, Department of Medicine and Hospitalist Programs, David Geffen School of Medicine at UCLA, Los Angeles, CA.

Correspondence to: Robert M. Strieter, MD, FCCP, 900 Veteran Ave, 14–154 Warren Hall, Los Angeles, CA 90095-1786; e-mail: rstrieter{at}mednet.ucla.edu

Idiopathic pulmonary fibrosis (IPF)/usual interstitial pneumonia (UIP) is not well-understood. Current explanations of the natural history and pathogenesis of IPF/UIP are controversial, and ongoing research continues to investigate multiple hypotheses. A complete understanding of the natural history of IPF could potentially help to identify different mechanisms that are operative at the early, intermediate, and end stages of the disease. This knowledge could lead to the development of more effective therapeutic interventions that target stage-specific aberrant pathways involved in IPF/UIP pathogenesis.

Key Words: idiopathic pulmonary fibrosis • natural history • pathogenesis • usual interstitial pneumonia • vascular remodeling






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2005 by the American College of Chest Physicians.