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(Chest. 2005;128:622S-628S.)
© 2005 American College of Chest Physicians

Clinical Challenges in Pulmonary Hypertension*

Roger S. Mitchell Lecture

Steeve Provencher, MD; Xavier Jais, MD; Azzedine Yaici, MD; Olivier Sitbon, MD; Marc Humbert, MD, PhD and Gérald Simonneau, MD

* From the Centre des Maladies Vasculaires Pulmonaires (UPRES EA 2705), Service de Pneumologie et Réanimation Respiratoire, AP-HP-Université Paris Sud XI, Hôpital Antoine Béclère, Clamart, France.

Correspondence to: Steeve Provencher, MD, Hôpital Antoine Béclère, 157 rue de la Porte de Trivaux, 92140 Clamart, France; e-mail: steeveprovencher{at}hotmail.com

Despite major advances in our understanding of the pathophysiologic processes leading to pulmonary arterial hypertension and recent developments in therapeutic approaches, the long-term prognosis for patients with pulmonary arterial hypertension remains unsatisfactory. Early detection and adequate clinical classification of the disease, better assessment of patients’ prognosis, and improved therapeutic strategies are important challenges for clinicians in coming years.

Key Words: chronic thromboembolic pulmonary hypertension • combination therapy • early detection • venoocclusive disease • walk test







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Copyright © 2005 by the American College of Chest Physicians.