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1. No chemotherapeutic agent or combination of agents will replace adequate surgical procedure and technique in the treatment of empyema.
2. Sodium tetradecyl sulfate, 1:500, in azochloramid, 1:3300, seems to be the best chemotherapeutic agent available in the treatment of acute pyogenic empyema, especially if bronchopleural fistula or mediastinal shift is present.
3. Azochloramid tetradecyl solution lowers surface tension, thereby allowing better penetration of the antiseptic agent and facilitates removal of the exudate. In addition, azochloramid tetradecyl sulfate solution tends to prevent reformation of intrapleural fluid while sterilizing the area.
4. Close attention must be given to the mechanical aspect of the pleural cavity.
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