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1. Data are presented to show that over half of the school population of the Phoenix area is sensitive to coccidioidin. Therefore, infection must usually take place in childhood.
2. A series of cases of clinical infection is presented in table form. The incidence is extremely low considering the number of sensitized individuals.
3. Infection is usually mild and self-limited. Relatively few cases can be proved beyond question. Serious disabling disease from the infection is extremely rare.
4. Two fatal cases have been reported in Phoenix, one of which is presented.
5. Most diagnoses of coccidioidomycosis infection must be presumptive rather than absolute as the period of sputum production is usually short and sputum cultures are required.
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