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* From Departments of Pulmonary Rehabilitation (Drs. Crisafulli and Clini, and Ms. Eutropio) and Oncology, Haematology, and Pneumology (Dr. Fabbri and Ms. Costi), University of Modena; Clinic Center Private Hospital (Dr. De Blasio and Mr. Penza), Pulmonary Rehabilitation Unit, Napoli; and Department of Pulmonary Rehabilitation (Drs. Biscione, Pasqua, and Ms. Americi), IRCCS San Raffaele, Velletri, Rome, Italy.
Correspondence to: Enrico M. Clini, MD, FCCP, University of Modena-Reggio Emilia, Department of Pulmonary Rehabilitation, Ospedale Villa Pineta, Italy, Via Gaiato 127, 41026 Pavullo n/F (MO); e-mail: clini.enrico{at}unimore.it
Abstract
Study objectives: To elucidate whether a simple walking aid may improve physical performance in COPD patients with chronic respiratory insufficiency who usually carry their own heavy oxygen canister.
Design: Randomized crossover trial.
Setting: Physiopathology laboratory of three rehabilitation centers.
Patients and interventions: We studied 60 stable COPD patients (mean age, 70.6 ± 7.9 years; FEV1, 44.8 ± 14.3% of predicted [± SD]) with chronic respiratory insufficiency who randomly performed, on 2 consecutive days, a standardized 6-min walking test using two different modalities: a full-weight oxygen canister transported using a small wheeled cart and pulled by the patient (Aid modality) or full-weight oxygen canister carried on the patients shoulder (No-Aid modality).
Measurements and results: The distance walked, peak effort dyspnea, and leg fatigue scores as primary outcomes, and other cardiorespiratory parameters as secondary outcomes were recorded during both tests. A significant difference (p < 0.05) between the two tests occurred for all the measured outcomes in favor of the Aid modality. Most importantly, significant changes for distance (+ 43 m, p < 0.001), peak effort dyspnea ( 2.0 points, p < 0.001), leg fatigue ( 1.4 points, p < 0.001), as well as for mean and nadir oxygen saturation and heart rate with the Aid modality (but not with the No-Aid modality) were recorded in the subgroup of patients walking < 300 m at baseline.
Conclusions: This study suggests that a simple walking aid may be helpful in COPD patients receiving long-term oxygen therapy, particularly in those with lower residual exercise capacity.
Key Words: exercise 6-min walking test symptoms wheeled cart
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