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(Chest. 1949;15:432-435.)
© 1949 American College of Chest Physicians

Streptomycin in Tuberculosis of the Larynx

BERNARD MARGULIES M.D.

1) Small and intermittent doses of streptomycin down to 0.2 gram daily, will give the same clinical improvement in cases of laryngeal tuberculosis as larger doses, and, will especially relieve the severe pain as in the larger doses.

2) A large percentage of recurrences of the disease may occur no matter what dose is used originally.

3) Toxicity is negligible with the smaller and intermittent doses, but the tubercle bacilli develop a resistance to small doses just as they do toward larger doses of streptomycin.






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Copyright © 1949 by the American College of Chest Physicians.