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(Chest. 1949;15:471-479.)
© 1949 American College of Chest Physicians

Lipoid Pneumonia in Neuropsychiatric and Debilitated Patients

ARTHUR A. HUMPHREY M.D.1 and EDWIN G. OLMSTEAD M.D.2

1 Consultant in Pathology, Veterans Hospital, Fort Custer, Michigan.
2 Physician in charge of Laboratory and X-ray Services, Veterans Hospital, Fort Custer, Michigan.

1) Four cases of lipoid pneumonia in neuropsychiatric and debilitated patients are presented which represented 5.4 per cent in a series of seventy-three autopsies.

2) The diagnosis is based upon a history of ingestion of oily substances, repeated bouts of pneumonia, the demonstration of oily droplets in the sputum following a lipoid-free diet, and the x-ray findings.

3) The x-ray findings are not specific but they are characteristic in the sense that they are persistent even though the patient may be asymptomatic.

4) Pathologically the gross appearance of the lungs is highly suggestive and the microscopic findings are specific.

5) A particularly destructive type of lipoid pneumonia is demonstrated when the mineral oil is employed as a vehicle for phenophthalein.

6) Treatment consists primarily in prophylaxis.






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Copyright © 1949 by the American College of Chest Physicians.