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(Chest. 1949;16:590-599.)
© 1949 American College of Chest Physicians

Results of Oral BCG Vaccination on 348 Families

AFFONSO MAC DOWELL M.D., F.C.C.P.

1) For the comparative study between vaccinated and nonvaccinated children, the investigation by families favors, without any doubt, a collection of more precise data than that carried out from heterogeneous sources.

2) Even so, certain items are profoundly divergent, and in both groups, with the sole exception of the greater incidence of known contagion in the nonvaccinated group, all the other factors were of a nature to cause a greater severity in the judgement of the results of the vaccinated cases as contrasted with the nonvaccinated cases.

3) The tuberculosis morbidity was of 3.13 per cent for the vaccinated group and 13.44 per cent for the control group, or, in other words, 4.2 times greater in the control group. The test X2 with the Yates correction for the verification of the significance was equal to 31.6.

4) The specific mortality, like the morbidity, was also 4.2 times greater in the control group. In view of the small numbers found here, the X2 test showed here the non-existence of significance.







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Copyright © 1949 by the American College of Chest Physicians.