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(Chest. 1950;18:93-97.)
© 1950 American College of Chest Physicians

The Use of PAS in the Treatment of Draining Tuberculous Empyemata

M. R. LICHTENSTEIN M.D., F.C.C.P.1 and PAUL ALFANO M.D.2

1 Chief of Medical Service, The Clinical and Research Departments of the City of Chicago Municipal Tuberculosis Sanitarium.
2 The Clinical and Research Departments of the City of Chicago Municipal Tuberculosis Sanitarium.

1) This report describes studies of 22 patients with tuberculous empyemas, draining through thoracotomies. One-half of the patients were treated for 120 days with oral PAS, the other half with a placebo. Local packs of 5 per cent of the sodium salt of PAS were used for 60 days on eight patients, saline packs on others.

2) PAS therapy produced no significant improvement in the treated cases as compared with the untreated.

3) Local packs of the sodium salt of PAS caused some thinning and diminution in the amount of the draining pus, and produced a cleaner appearing wound.

4) Constitutional improvement was slight.






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Copyright © 1950 by the American College of Chest Physicians.