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1 Chief of Medicine, The Department of Medicine, U. S. Marine Hospital, Staten Island, New York.
2 Deputy Chief of Medicine, The Department of Medicine, U. S. Marine Hospital, Staten Island, New York.
3 Senior Medical Resident, The Department of Medicine, U. S. Marine Hospital, Staten Island, New York.
1) Three patients with long-standing bronchial asthma were treated with cortisone by inhalation, without demonstrable effect.
2) This method of therapy was compared with parenteral cortisone administration in two of these patients.
3) Several reasons are postulated to explain the lack of response to nebulized cortisone in contrast to the favorable response obtained with parenteral cortisone.
4) The observations recorded are the initial results of a continuing study. Further investigation seems warranted.
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