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1 The Departments of Medicine and Pathology, National Jewish Hospital at Denver, and the University of Colorado School of Medicine.
During the past few years we have witnessed an ever growing knowledge of the cardio-pulmonary system. It has become possible to explain on a sound physiological basis many of the hitherto obscure phenomena concerned in the regulation of the pulmonary circulation. The exact significance of much of the data gathered in studying chronic pulmonary disease, however, still cannot be correlated satisfactorily. While it may be concluded that the disease alterations of the vascular bed must play a large role in the development of pulmonary hypertension, its exact position in the problem cannot be assessed adequately.
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