Intralobar Pulmonary Sequestration

¹ The Hospital for Sick Children, Toronto, and the Pediatric Department of the University of Toronto.

1) Six further cases of a congenital lung anomaly of both teratological and clinical interest are described.

2) The anomaly consists of a portion of displaced lung tissue in the chest cavity with hypoplastic alveoli and dilated bronchi which give the lung its honeycombed or cystic appearance. This displaced lung is the recipient of a systemic vascular supply usually from the aorta. It has come to be called intralobar sequestration since Pryce's paper was published.

3) It is probably due to the amputation of a primordial lung bud by an aberrant artery, occurring in the 4 to 14 mm. embryo.

4) The history, physical findings, and radiographic changes which make its diagnosis easy, are discussed. The clinical importance of its correct diagnosis is indicated.

5) Three cases are mentioned in which the whole lung was involved in the process and the question raised if such a result could not ensue rather than agenesis when earlier more massive portions of the bronchial tree are amputated.