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(Chest. 1954;26:264-267.)
© 1954 American College of Chest Physicians

Peripheral Neuritis Due to Hydrazide Derivatives

SOL KATZ M.D., F.C.C.P.1; ROBERT GRUVER M.D.1; BUSHNELL SMITH M.D.1; and GEORGES McCORMICK M.D.1

1 The Pulmonary Disease Division and the Department of Neurology, District of Columbia General Hospital and the Departments of Medicine, Georgetown University School of Medicine and George Washington University School of Medicine, Washington, D. C.

Peripheral neuritis following isoniazid has been observed in 19 patients. The chief components are paresthesias of both upper and lower extremities. There was no strict correlation between duration of therapy and onset and severity of symptoms. In most instances symptoms gradually subsided following cessation of the drug.







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